Eur J Musculoskel Dis 2025 May-Aug;14(2):65-75


ARTICLE

PATIENT ON DUAL ANTIPLATELET THERAPY: ASSESSMENT OF BLEEDING RISK AND ITS MANAGEMENT IN MINOR ORAL SURGERY WITH A FOCUS ON EXTRACTION SURGERY

S. Lauri1, M. Scarpati Cioffari di Castiglione2*, A. Coppola3, A. Della Corte4, A. Danieli5, C. Moscetta6, I. Mastrorilli7 and P. Poliçi8

1 Independent researcher, 00073, Rome, Italy;
2 Independent researcher, 81021, Caserta, Italy;
3 Dentistry and Implantology, Studio Armando Coppola, Corso Garibaldi 246, Naples, Italy;
4 Independent researcher,72021, Brindisi, Italy;
5 Independent researcher, 00010, Rome, Italy;
6 Independent researcher, 03018, Frosinone, Italy;
7 Independent researcher, 00135, Rome, Italy;
8 Catholic University Our Lady of Good Counsel, Tirana, Albania.

*Correspondence to:
Maria Scarpati Cioffari di Castiglione,
Independent Researcher,
81021 Caserta, Italy.
e-mail: mariascarpati98@gmail.com

Received: 15 July, 2025
Accepted: 30 August, 2025
 
ISSN 2975-044X (online) ISSN 2038-4106 (print)
Copyright © by BIOLIFE 2025
This publication and/or article is for individual use only and may not be further reproduced without written permission from the copyright holder. Unauthorized reproduction may result in financial and other penalties. Disclosure: All authors report no conflicts of interest relevant to this article.

ABSTRACT

Background: Antiplatelet drugs are widely used to prevent and treat ischemic cardio-cerebrovascular conditions by inhibiting platelet aggregation and reducing thrombotic events. However, their use poses significant challenges in dental procedures due to the increased risk of bleeding. Materials and Methods: This study evaluates the safety of dental extractions in patients on dual antiplatelet therapy (DAPT) through clinical and statistical analysis of 48 patients undergoing 71 tooth extractions. Appropriate local hemostatic measures were employed to manage bleeding risks. Results: The results indicate that, with appropriate local hemostatic measures, dental extractions can be safely performed without significant hemorrhagic complications. The study highlights the importance of personalized patient management, especially in the presence of periodontal inflammation, to minimize bleeding risks. Conclusions: The findings support the continuation of antiplatelet therapy during minor oral surgeries, emphasizing the need for careful planning and collaboration with cardiologists to balance bleeding risks and thrombotic prevention.

KEYWORDS: Antiplatelet drugs, dual antiplatelet therapy, dental extractions, bleeding risk, hemostatic measures, periodontal inflammation, patient management

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